| Nitrogen mustards | Bendamustine (Treanda, Bendeka) Chlorambucil (Leukeran) CycloPHOSphamide (Cytoxan, Neosar) Ifosfamide (Ifex) Mechlorethamine (Topical for CTCL; Valchlor) Melphalan (Alkeran, Evomela) Melphalan flufenamide (Pepaxto; withdrawn 2022) |
| Nitrosureas | Carmustine (BiCNU, Gliadel Wafer [brain tumors]) Lomustine (CeeNU, Gleostine) Streptozocin (Zanosar) |
| Platinum analogs | CISplatin (Platinol) CARBOplatin (Paraplatin) Oxaliplatin (Eloxatin) |
| Triazenes | Dacarbazine (DTIC-Dome) Temozolomide (Temodar) |
| Alkyl Sulfonates | Busulfan (Myleran PO, Busulfex IV) Treosulfan |
| Ethyleneimines | Thiotepa (Tepadina) |
| Methylmelamine | Altretamine (Hexalen) |
| Methylhydrazine derivative | Procarbazine (Matulane) |
| Marine-derived / minor groove binders | Trabectedin (Yondelis) Lurbinectedin (Zepzelca for SCLC) |